NCT00551837

Immune Response to Influenza Vaccination

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 82 (actual)
• Sponsor: The Cleveland Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the immune response to a routine influenza vaccination. Influenza vaccination is given as part of routine standard of care in these individuals and is not part of the study protocol. The study will evaluate for a change in response to common antigens over time after influenza vaccination to determine if changes are related to the development of chronic rejection after solid-organ transplantation. We hypothesize that the influenza vaccine contributes to the alloreactivity of T cells verses common HLA types in the donor pool.

Conditions

• Solid Organ Transplantation
• Chronic Kidney Disease

Timeline

• Start date: 2006-11-01
• Primary completion: 2008-04-01
• Completion: 2008-05-01
• First posted: 2007-10-31
• Last updated: 2017-10-24