NCT00549419

Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal Surgery

Randomized Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Patients Undergoing Major Abdominal Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Klinikum Ludwigshafen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether the early identification and more precise intervention of goal-directed intraoperative plasma volume expansion and catecholamine therapy using arterial pressure based cardiac output (APCO) measurement in addition to normal vital signs will improve postoperative organ function, in particular renal function, in patients undergoing major abdominal surgery.

Conditions

• Major Abdominal Surgery

Interventions

Type	Name	Description
DRUG	Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine	The Control group will be assessed using the standard care of traditional vital signs
DRUG	Goal-directed hemodynamic therapy	Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine
DRUG	Standard of care	Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine

Timeline

• Start date: 2007-10-01
• Primary completion: 2009-01-01
• Completion: 2009-04-01
• First posted: 2007-10-25
• Last updated: 2009-12-23

Locations

1 site across 1 country: Germany