NCT00548678

Platelet Function and Safety After IV and Oral Diclofenac, IV Ketorolac and Oral Aspirin in Adult Volunteers

Open-Label, Randomized, Single-Dose, Four-Treatment Crossover Study to Evaluate Platelet Function in Healthy Adult Males After Administration of IV Diclofenac Sodium, Oral Diclofenac Potasssium, IV Ketorolac Tromethamine, and Acetylsalicylic Acid

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Javelin Pharmaceuticals · Industry
• Sex: Male
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study will assess platelet function and safety in healthy male volunteers following doses of intravenous diclofenac compared to oral diclofenac (Cataflam), intravenous ketorolac and oral aspirin.

Detailed description

The primary objective is to evaluate platelet function following intravenous diclofenac, oral diclofenac (Cataflam), intravenous ketorolac and oral aspirin.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	intravenous diclofenac sodium (DIC075V)	intravenous diclofenac sodium
DRUG	ketorolac	intravenous ketorolac
DRUG	oral diclofenac (Cataflam)	oral diclofenac (Cataflam)
DRUG	aspirin	oral aspirin

Timeline

• Start date: 2007-10-01
• Primary completion: 2007-11-01
• Completion: 2007-11-01
• First posted: 2007-10-24
• Last updated: 2008-07-16

Locations

1 site across 1 country: United States