NCT00548132

Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,088 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

We proposed to perform a prospective randomized controlled trial to study the effect of the use of a commercially-available chlorhexidine-impregnated sponge (Biopatch) as part of central venous catheter care on catheter-related bloodstream infections among patients in two Barnes-Jewish Hospital ICUs.

Detailed description

At the time of the inception of this study, there were no published randomized controlled trial on the efficacy of the Biopatch in reducing bloodstream infections. Preliminary data has shown that the Biopatch decreases colonization of the catheter exit site and thereby decrease bloodstream infections but this was at that time only theoretical.

Conditions

• Catheter-related Bloodstream Infection

Interventions

Type	Name	Description
DEVICE	Chlorhexidine-impregnated foam dressing	Patients in the treatment arm will have the Biopatch incorporated into their catheter care protocol. ICU nurses were instructed on the proper use of this novel dressing/sponge. Catheter dressing changes will only be done every 7 days unless there is visible blood, soiling underneath the dressing, or if the dressing comes off.

Timeline

• Start date: 2006-02-01
• Primary completion: 2008-02-01
• Completion: 2009-05-01
• First posted: 2007-10-23
• Last updated: 2013-09-12
• Results posted: 2013-08-22

Locations

1 site across 1 country: United States