NCT00542516

Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty

Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty: Hydroxyethyl Starch Versus Ringer's Lactate

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate. This research has been analyzing hemodynamic parameters and the coagulation status before and after the pre-expansion with the solutions above mentioned.

Detailed description

This trial is randomized an blind to the physician who is analyzing the results.It has been select adults; both sex; ASA I and II. These patients must be submitted to hip arthroplasty replacement. The anesthesia technique is single shot spinal anesthesia. Primary endpoint: assessment alternative; technique replacement volemic with HES 130/04. Secondary endpoint: haemostatic abnormalities; blood loss; transfusion blood.

Conditions

• Hip Replacement Arthroplasty

Interventions

Type	Name	Description
DRUG	Hydroxyethyl Starch	Dosage: 30ml/kg; frequency: one time; duration: 60min
DRUG	Ringer's lactate	Dosage: 30ml/kg; frequency: one time; duration: 60min.After 10ml-kg-h both groups

Timeline

• Start date: 2006-09-01
• Completion: 2008-11-01
• First posted: 2007-10-11
• Last updated: 2009-02-19

Locations

1 site across 1 country: Brazil