Clinical Trials Directory

Trials / Completed

CompletedNCT00533793

Adjunctive Therapy to Treat Tibial Shaft Fractures

A Phase II Randomized, Controlled, Open-labeled (Dose-blinded) Dose Finding Study of the Safety and Efficacy of I-040202 in the Treatment of Patients With Acute Open Tibial Shaft Fractures

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
201 (actual)
Sponsor
Kuros Biosurgery AG · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A phase 2, prospective, randomized, controlled, open-label (dose-blinded), parallel group, international multi-center study. The study will consist of four treatment groups - one control group (SoC) and three I-040202 groups receiving SoC plus 0.133 mg/mL, 0.4 mg/mL or 1.0 mg/mL I-040202.

Conditions

Interventions

TypeNameDescription
PROCEDUREopen fracture reductioninternal fracture fixation: osteosynthesis plates or intra-medullary nails

Timeline

Start date
2007-04-01
Primary completion
2011-05-01
Completion
2011-05-01
First posted
2007-09-21
Last updated
2012-03-16

Locations

49 sites across 12 countries: Bulgaria, Czechia, Finland, France, Germany, Hungary, Italy, Romania, Serbia, Slovakia, Slovenia, Switzerland

Source: ClinicalTrials.gov record NCT00533793. Inclusion in this directory is not an endorsement.