NCT00532402

Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas

Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas - Compared With Propofol Concentration in Plasma (Before and) After Lung Passage and Neurophysiological Parameters

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 16 (estimated)
• Sponsor: University of Luebeck · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study should compare the propofol concentration in breathing gas and in plasma (before and) after lung passage. Propofol concentrations in breathing gas are continuously measured by a sensor. For comparison a discontinuous method is used. Neurophysiologic parameters for determination of depth of anesthesia are compared to the continuous measured propofol concentration in breathing gas. Study hypothesis: continuous measured propofol concentration in breathing gas correlates to propofol concentration in plasma and depth of anaesthesia.

Conditions

• General Anesthesia

Timeline

• Start date: 2007-09-01
• Completion: 2010-12-01
• First posted: 2007-09-20
• Last updated: 2012-10-30

Locations

2 sites across 1 country: Germany