NCT00532142

The ROVO Study: Radial Optic Neurotomy for CVO

A Multicenter Trial for Surgical Treatment of Central Retinal Vein Occlusion - Radial Optic Neurotomy for CVO The ROVO Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: —
• Sponsor: Rudolf Foundation Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The ROVO study is a prospective, placebocontrolled and randomised study designed to evaluate the effect of radial optic neurotomy in central vein occlusion, versus triamcinolone acetonide. 240 patients with a visual acuity \< 0.5 Snellen will be randomised. Patients are treated with either RON, or a single intravitreal injection of 4 mg triamcinolone acetonide, or a placebo treatment - a "sham" injection of intravitreal triamcinolone. Patients will be examined regularly over a period of one year. Best corrected visual acuity for far and near, as well as clinical examinations, fluorescein- and indocyanine green angiograms, optical coherence tomography, and perimetry, are performed pre- and postoperatively.

Conditions

• Central Retinal Vein Occlusion

Interventions

Type	Name	Description
DRUG	Intravitreal Triamcinolone
PROCEDURE	Radial Optic Neurotomy
OTHER	Placebo - Sham Intravitreal Injection

Timeline

• Start date: 2005-04-01
• Completion: 2009-08-01
• First posted: 2007-09-20
• Last updated: 2009-10-30

Locations

1 site across 1 country: Austria