NCT00530972

Pilot Study of Patients Chronic Hepatitis C in Co-infected HIV Patients Relapsers After Previous Therapies

Treatment of Patients With Chronic Hepatitis C Co-infected With HIV Relapsers or Non Responders, Previous Exposed to Sub-optimal Therapies: Open, Pilot Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Hospital Carlos III, Madrid · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To determine the efficacy and safety of Peginterferón alfa-2a (40 KD) plus Ribavirin in patients who have relapsed or not responded to a previous suboptimal therapy based in Interferon.

Detailed description

An important number of co-infected patients were treated suboptimally in the past with others ineffective therapies interferon-based. All co-infected patients should be an opportunity of retreatment with actually therapies.

Conditions

• Chronic Hepatitis C
• HIV Infections

Interventions

Type	Name	Description
DRUG	Peginterferon alfa-2a plus ribavirin adjusted to body weight	PegInterferon 180 mcg/week, Adjusted body weight Ribavirin (1000 mg \<75 kg, 1200 mg \>75 kg)

Timeline

• Start date: 2006-03-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2007-09-18
• Last updated: 2009-09-07

Locations

1 site across 1 country: Spain