Trials / Completed
CompletedNCT00529828
Health Effects of CLA Versus Industrial Trans Fatty Acids
Health Effects of CLA Versus Industrial Trans Fatty Acids in Healthy Volunteers (CLARINeT-Study)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Wageningen University · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The knowledge of the health effects of CLA on the human body is limited. However, CLA supplements are sold over the counter in several countries and various techniques are used to increase the content of CLA in food. The CLARINeT study will be performed to investigate the effect of CLA on blood lipoproteins, inflammatory markers, blood pressure and insulin status in human volunteers relative to industrial trans fatty acids and to oleic acid.
Detailed description
It will be a double-blind randomized multiple cross-over trial with 3 treatments: * CLA; * Industrial trans fatty acids (as a positive control); * Oleic acid (Cis 18:1, the monounsaturated fatty acid in unhydrogenated vegetable oils) as a reference fat. Each volunteer receives each diet for three weeks, in random order, for a total of 9 weeks. Three weeks is sufficient to reach new stable lipoprotein levels.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Consumption of CLA enriched food |
Timeline
- Start date
- 2007-09-01
- Primary completion
- 2008-01-01
- Completion
- 2008-01-01
- First posted
- 2007-09-14
- Last updated
- 2008-01-16
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT00529828. Inclusion in this directory is not an endorsement.