NCT00529542

A Trial of Lipitor (Atorvastatin) for the Treatment of Polycystic Ovary Syndrome (PCOS) in Women With Elevated Low-density Lipoprotein (LDL) Cholesterol

A Six-week Double Blinded, Randomized Trial of Atorvastatin for the Treatment of PCOS Women With Elevated LDL Cholesterol

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the efficacy of Lipitor (Atorvastatin) for the treatment of PCOS with elevated LDL cholesterol.

Detailed description

The investigators hypothesize that improving the lipid profile with atorvastatin will improve vascular function, increase the frequency of ovulation, decrease androgen levels, improve insulin sensitivity, and improve the lipid profile more efficiently than placebo.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
DRUG	Lipitor	40mg caplets per day for six weeks
DRUG	Placebo	1 placebo caplet per day for six weeks.

Timeline

• Start date: 2004-12-01
• Primary completion: 2010-08-01
• Completion: 2010-08-01
• First posted: 2007-09-14
• Last updated: 2014-09-25
• Results posted: 2013-05-08

Locations

1 site across 1 country: United States