NCT00525772

Effect of Ciclesonide on Exercise Induced Bronchoconstriction

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Hamilton Health Sciences Corporation · Academic / Other
• Sex: All
• Age: 12 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to study the effects of once daily inhaled ciclesonide at varying doses on exercise provoked asthma symptoms, fall in lung function after exercise and sputum characteristics.

Detailed description

To study the effects of 4 doses of ciclesonide on exercise-induced bronchoconstriction, bronchial responsiveness to mannitol, sputum parameters and other parameters of asthma control in asthmatic patients. The primary aim was to evaluate exercise-induced bronchoconstriction as a method of determining the dose and time responses of inhaled corticosteroid therapy. The secondary aims were to evaluate the dose and time responses of sputum parameters and responsiveness to mannitol to inhaled corticosteroid therapy. Furthermore to explore the relationship(s) between exercise induced bronchoconstriction, sputum parameters and mannitol responsiveness.

Conditions

• Asthma

Interventions

Type	Name	Description
DRUG	ciclesonide	low dose- 50ug and 200ug
DRUG	ciclesonide	high dose- 100ug and 400ug

Timeline

• Start date: 2001-11-01
• Primary completion: 2007-11-01
• Completion: 2007-11-01
• First posted: 2007-09-06
• Last updated: 2009-10-21

Locations

1 site across 1 country: Canada