Trials / Completed
CompletedNCT00524693
Montelukast in Acute RSV Bronchiolitis
A Double-Blind Placebo Controlled Randomized Trial of Montelukast in Acute Respiratory Syncytial Virus Bronchiolitis
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 51 (actual)
- Sponsor
- Ziv Hospital · Other Government
- Sex
- All
- Age
- 4 Weeks – 2 Years
- Healthy volunteers
- —
Summary
There is evidence of inflammatory mechanisms in RSV bronchiolitis with increased cysteinyl-leukotrienes (cys-LT). Recently, specific cys-LT receptor antagonists - montelukast (Singulair©) approved for use in infants as granule sachets, have become available. We evaluated the effect of Singulair© on clinical progress and on cytokine profiles in the acute phase of RSV bronchiolitis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Montelukast | 4mg sachets |
| DRUG | Placebo granules |
Timeline
- Start date
- 2006-01-01
- First posted
- 2007-09-05
- Last updated
- 2007-09-05
Source: ClinicalTrials.gov record NCT00524693. Inclusion in this directory is not an endorsement.