Trials / Completed
CompletedNCT00524212
How to Improve Diagnosis in Infective Endocarditis
Ph. D Student, Jane Byriel Knudsen, Aarhus University
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 761 (actual)
- Sponsor
- University of Aarhus · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose is to exam prospective if simple clinical information in combination with a normal s-procalcitonin are sufficient for exclusion of infective endocarditis (IE).
Detailed description
Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality. The variable clinical presentation of IE makes the diagnosis a clinical challenge. Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections. The purpose of this study is: * to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected. * to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
Conditions
Timeline
- Start date
- 2007-03-01
- Completion
- 2009-05-01
- First posted
- 2007-09-03
- Last updated
- 2010-01-20
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT00524212. Inclusion in this directory is not an endorsement.