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UnknownNCT00522977

Echo-Cardiographic Assessment of Cardiovascular Characteristics During Pregnancy and Postpartum Periods

Status
Unknown
Phase
Study type
Observational
Enrollment
400 (estimated)
Sponsor
Hillel Yaffe Medical Center · Other Government
Sex
Female
Age
Healthy volunteers
Accepted

Summary

The purpose of this echocardiographic study is to restudy the longitudinal changes in cardiac size and function during and after pregnancy in healthy women using relatively new parameters of systolic and diastolic function as well as classical measures of left ventricle (LV) function using contemporary echocardiographic machines. We, the researchers at Hillel Yaffe Medical Center, will assess diastolic function and its possible relation to shortness of breath.

Detailed description

A comprehensive echocardiographic study of the heart will be conducted in the first, second and third trimesters of pregnancy and 3 months postpartum. Determination of left ventricular dimensions, transvalvular Doppler flow, ejection fraction, stroke volume, cardiac output, pulmonary vein flow, tissue Doppler, flow propagation, global and segmental strain parameters, timing of peak strain and various parameters of diastolic function will be obtained. From these data normal values for various stages of pregnancy will be determined as well as range for changes expected during longitudinal follow-up will be determined.

Conditions

Timeline

Start date
2007-08-01
Completion
2009-09-01
First posted
2007-08-30
Last updated
2008-02-29

Locations

1 site across 1 country: Israel

Source: ClinicalTrials.gov record NCT00522977. Inclusion in this directory is not an endorsement.