Clinical Trials Directory

Trials / Completed

CompletedNCT00522145

Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib

A Phase 2 Study of XL647 in Subjects With Non-Small Cell Lung Cancer Who Have Progressed After Responding to Treatment With Either Gefitinib or Erlotinib

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
41 (actual)
Sponsor
Kadmon Corporation, LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the best confirmed response rate of daily administration of the multiple receptor tyrosine kinase (RTK) inhibitor (including EGFR and VEGFR2) XL647 in subjects with NSCLC who have progressed after responding to treatment with either erlotinib or gefitinib.

Conditions

Interventions

TypeNameDescription
DRUGXL647Daily dosing as a single oral agent at a dose of 300 mg supplied as 50-mg tablets

Timeline

Start date
2007-05-01
Primary completion
2009-10-01
Completion
2010-02-01
First posted
2007-08-29
Last updated
2022-05-13

Locations

10 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00522145. Inclusion in this directory is not an endorsement.