Clinical Trials Directory

Trials / Completed

CompletedNCT00520390

A Phase I, Study to Evaluate the Safety and Tolerability of Intravenous EZN-2208 in Patients With Advanced Solid Tumors or Lymphoma (EZN-2208-02)

A Phase I, Multicenter, Open-Label, Dose-Escalation Study Evaluating the Safety and Tolerability of Intravenous EZN-2208 PEG-SN38) Administered Weekly for 3 Weeks in 4-Week Cycles in Patients With Advanced Solid Tumors or Ymphoma (EZN-2208-02)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
34 (planned)
Sponsor
Enzon Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The goal of this clinical research study is to find the highest tolerable dose of EZN-2208 that can be given to patients with advanced cancer or lymphoma. The safety of the study drug and its effect on the disease will also be studied. Enzon will also perform pharmacokinetic (PK) testing of EZN-2208. PK testing measures the amount of a drug in the body at different time points.

Conditions

Interventions

TypeNameDescription
DRUGEZN-2208

Timeline

Start date
2007-05-01
First posted
2007-08-24
Last updated
2010-04-02

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00520390. Inclusion in this directory is not an endorsement.

A Phase I, Study to Evaluate the Safety and Tolerability of Intravenous EZN-2208 in Patients With Advanced Solid Tumors (NCT00520390) · Clinical Trials Directory