NCT00520338

Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether celecoxib is effective in the treatment postoperative pain after thyroidectomy. The research hypothesis: There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib or placebo.

Detailed description

Postoperative pain has been concerned in the past few years by both the anesthesiologists ans the surgeons. COX2-inhibitors have played an important roles in postoperative pain with minimal side effects. Comparison(s): There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib and placebo.

Conditions

• Postoperative Pain
• Thyroidectomy
• Cyclooxygenase 2 Inhibitors

Interventions

Type	Name	Description
DRUG	celecoxib	1. placebo 2. celecoxib 400 mg oral single dose

Timeline

• Start date: 2007-08-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2007-08-24
• Last updated: 2010-11-09

Locations

1 site across 1 country: Thailand