NCT00518830

Treatment of Postnatal Depression for Low-Income Mothers in Primary Care in Santiago, Chile

Randomized Clinical Trial for the Treatment of Postnatal Depression

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 230 (actual)
• Sponsor: Fondo Nacional de Desarrollo Científico y Tecnológico, Chile · Other Government
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A randomized clinical trial was carried out at primary care level in Santiago, Chile to investigate a combined treatment for women suffering post-natal depression and preventing the adverse consequences of this illness on infant's growth and development.

Detailed description

Background: We compared the effectiveness of a multi-component intervention with usual care to treat postnatal depression among low-income mothers in primary care clinics in Santiago, Chile. Methods: Randomised controlled trial. Two hundred and thirty mothers with major depression attending postnatal clinics were randomly allocated to either a multi-component intervention or usual care. The multi-component intervention involved a psychoeducational group, treatment adherence support, and pharmacotherapy if needed. Data were analysed on an intention-to-treat basis. The main outcome measure was the Edinburgh Postnatal Depression Scale (EPDS) at 3 and 6 months after randomisation.

Conditions

• Postnatal Depression

Interventions

Type	Name	Description
OTHER	multi-component intervention	The PND-MCI included psycho-educational groups, structured pharmacotherapy if needed, and systematic monitoring of clinical progress and treatment compliance
OTHER	Usual care	included all services normally available in the clinics, including antidepressant medication, brief psychotherapeutic interventions or referral for specialty treatment

Timeline

• Start date: 2004-03-01
• Completion: 2006-07-01
• First posted: 2007-08-21
• Last updated: 2007-08-21