Trials / Completed
CompletedNCT00518765
Hemodynamic Effects of Aliskiren Compared to Captopril on the Kidney in Healthy Volunteers on a Low- and High- Sodium Diet
A Single-center, Placebo-controlled Study of the Effects of Ascending Single Oral Doses of Aliskiren Compared With Captopril on Renal Hemodynamics in Healthy Volunteers on a Low and High Sodium Diet "Renin Inhibition and the Kidney"
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 32 (actual)
- Sponsor
- Novartis · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
This study will measure the effects of different doses of aliskiren on kidney blood flow and function in healthy adults and determine how salt intake affects the response to aliskiren.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Aliskiren | |
| DRUG | Aliskiren plus placebo | |
| DRUG | Aliskiren | |
| DRUG | Aliskiren plus placebo |
Timeline
- Start date
- 2005-10-01
- Primary completion
- 2007-08-01
- First posted
- 2007-08-21
- Last updated
- 2010-10-06
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00518765. Inclusion in this directory is not an endorsement.