Trials / Completed
CompletedNCT00517426
Effects of Acetazolamide and CO2 Inhalation on Exercise-induced Periodic Breathing in Heart Failure
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Centro Cardiologico Monzino · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate the effects of CO2 inhalation and acetazolamide treatment on exercise-induced periodic breathing in patients with chronic stable heart failure. Patients will be given CO2 (2%) during a constant workload exercise. Patients will be also evaluated by maximal cardiopulmonary exercise test without and with acetazolamide acute and chronic treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | acetazolamide | i.v. 500 mg of acetazolamide for the acute study and 500 mg of acetazolamide p.o. t.i.d. for two days |
Timeline
- Start date
- 2007-07-01
- Primary completion
- 2011-07-01
- Completion
- 2012-08-01
- First posted
- 2007-08-17
- Last updated
- 2016-01-28
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT00517426. Inclusion in this directory is not an endorsement.