NCT00516516

Oral Carnitine for Cramps in Pregnancy

Oral L-Carnitine for the Treatment of Muscle Cramps in Pregnancy: A Randomized, Controlled Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: Female
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

Muscle cramps occur frequently among pregnant women, and few therapeutic options exist. This is a study of oral L-carnitine, a dietary supplement, for the treatment of muscle cramps in pregnancy. Our hypothesis is that carnitine will alleviate or eliminate muscle cramps experienced by pregnant women.

Detailed description

Muscle cramps occur frequently among pregnant women, and few therapeutic options exist. This is a study of oral L-carnitine, a dietary supplement, for the treatment of muscle cramps in pregnancy. The conceptual basis for this study comes from the fact that carnitine has been used effectively in multiple randomized trials for the treatment of muscle cramps in other carnitine deficient states (such as hemodialysis). In pregnancy, women have decreased serum carnitine concentrations (from decreased intake, increased clearance by the kidney, and increased demands from the fetus). Thus, our hypothesis is that carnitine will alleviate or eliminate muscle cramps experienced by pregnant women.

Conditions

• Muscle Cramp

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	L-Carnitine	L-Carnitine, 1g orally, twice daily
DIETARY_SUPPLEMENT	Placebo	Placebo, similar in appearance to study tablets, given orally, twice daily.

Timeline

• Start date: 2008-07-01
• Primary completion: 2009-06-01
• Completion: 2009-07-01
• First posted: 2007-08-15
• Last updated: 2017-04-20

Locations

3 sites across 1 country: United States