Trials / Unknown
UnknownNCT00516230
Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (estimated)
- Sponsor
- Samsung Medical Center · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.
Detailed description
Patients with newly diagnoised colorectal cancer will be eligible. They will undergo detailed history taking including family history, and molecular stuidies including microsatellite instability test and immunohistochemistry for DNA mismatch repair protein with pre-selection. Any abnormal finding in molecular stuides will be offered genetic testing (after testing methylation status for patients with abnormalities in MLH1).
Conditions
Timeline
- Start date
- 2006-01-01
- Completion
- 2011-12-01
- First posted
- 2007-08-15
- Last updated
- 2007-08-15
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT00516230. Inclusion in this directory is not an endorsement.