NCT00513019

Double-Blind Lamictal (Lamotrigine) in Neurotic Excoriation

A Double-Blind Study of Lamictal in Neurotic Excoriation

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of the proposed study is to evaluate the comparative efficacy of Lamictal (lamotrigine) to placebo in neurotic excoriation. Thirty subjects with neurotic excoriation will receive 12 weeks of double-blind treatment with Lamictal (lamotrigine) or matching placebo. The hypothesis to be tested is that Lamictal (lamotrigine) will be more effective than placebo in patients with neurotic excoriation. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Detailed description

The study will consist of 12 weeks of double-blind treatment with Lamictal (lamotrigine) compared to placebo (1:1) in 30 subjects with neurotic excoriation.

Conditions

• Neurotic Excoriation
• Pathologic Skin Picking
• Psychogenic Excoriation
• Dermatillomania

Interventions

Type	Name	Description
DRUG	Lamictal (lamotrigine)	once daily from beginning to end of study. Dosage varies.
DRUG	Placebo	daily

Timeline

• Start date: 2007-08-01
• Primary completion: 2009-08-01
• Completion: 2009-09-01
• First posted: 2007-08-08
• Last updated: 2023-02-23
• Results posted: 2013-09-27

Locations

1 site across 1 country: United States