NCT00512226

Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia

Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia Using T2* Cardiac MRI.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: HaEmek Medical Center, Israel · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Iron overload is well study in Thalassemia patients and it's not only related to blood transfusions, since intestinal iron absorption is also increased in those patients. Sickle cell patients didn't develope significant clinical symptoms and signs of iron overload in spite frequent transfusions. The purpouse of this study is to assess the iron overload in Sickle cell anemia and Sickle cell Thalassemia patients using clinical parameters and cardiac T2\*MRI in order to determine the cardiac and liver iron.

Conditions

• Sickle Cell Anemia
• Sickle Cell Thalassemia
• Iron Overload
• MRI

Interventions

Type	Name	Description
OTHER	Cardiac and Liver T2* MRI	Laboratory examinations that are routinely used in follow up of those patients and T2\* MRI analysis.

Timeline

• Start date: 2007-09-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2007-08-07
• Last updated: 2011-08-26

Locations

1 site across 1 country: Israel