NCT00511537

Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders

Standard of Care Trial: Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 16 Years – 54 Years
• Healthy volunteers: Not accepted

Summary

This study performs HLA matched stem cell transplantation from unrelated donors in adults who require stem cell transplantation but do not have a matched related donor available. The incidence of graft-versus-host disease in unrelated stem cell transplantation is recorded. This study also monitors the activity and toxicity of total body irradiation and cyclosphosphamide followed by stem cell transplantation from matched unrelated donors.

Detailed description

This protocol identifies a standard-of-care method for unrelated stem cell transplantation in adults. Performing this service in a consistent and documented fashion allows investigators to obtain informed consent from recipients. Data is tabulated locally for quality-control comparisons with nationally-reported standards. As a condition of maintaining transplant center status and to have acess to NMDP-registered donors, UCSF submits clinical and outcome data to the NMDP. As a result, UCSF is contributing to the resolution of remaining uncertainties regarding particular transplantation practices.

Conditions

• CML
• ALL
• AML
• Myelodysplasia
• Lymphoma
• Myeloproliferative Disorders

Timeline

• Start date: 1999-01-01
• Primary completion: 2009-06-01
• Completion: 2009-06-01
• First posted: 2007-08-06
• Last updated: 2013-08-02

Locations

1 site across 1 country: United States