NCT00511225

Effects of Oral Cholecalciferol (Vitamin D3) on Bone Health, Neuromuscular Function, and Quality of Life in Adults With Chronic Kidney Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: Creighton University · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Will oral vitamin improve strength, bone quality, pain and quality of life. This is a double blind, randomized placebo controlled study using 10,000 IU of cholecalciferol vs placebo.

Detailed description

The proposed study is be a randomized, double-blind, placebo-controlled trial of supplementation with oral vitamin D3. Each subject will take a once-weekly capsule containing vitamin D3 or a an identical-appearing placebo for a treatment period of 15 weeks. Subjects will be assessed for Bone pain and tenderness, Neuromuscular function, physical performance score, and Quality of life assessment. A subset of subjects will have bone biopsies performed before and after intervention.

Conditions

• End Stage Renal Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	cholecalciferol	10,000 IU weekly
DIETARY_SUPPLEMENT	placebo	placebo capsule

Timeline

• Start date: 2007-09-01
• Primary completion: 2010-06-01
• Completion: 2011-09-01
• First posted: 2007-08-03
• Last updated: 2012-07-03

Locations

1 site across 1 country: United States