NCT00510666

Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy

Butorphanol and Tramadol for Morphine PCA Pain Management After Total Hysterectomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 841 (actual)
• Sponsor: Nanjing Medical University · Academic / Other
• Sex: Female
• Age: 19 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients underwent different anesthesia treatments remains unknown explicitly. The investigators hypothesized that butorphanol and tramadol can produce different analgesic effects with intravenous PCA after abdominal hysterectomy.

Conditions

• Postoperative Pain
• Hysterectomy

Interventions

Type	Name	Description
DRUG	Saline	Saline infusion adjunct to morphine PCA pump
DRUG	Butorphanol tartrate	Butorphanol was delivered at a continuous infusion manner adjunct to morphine PCA pump
DRUG	Tramadol Hydrochloride	100mg tramadol was used preemptively to morphine PCA pump
DRUG	Saline	Preemptive saline as a control group to tramadol one

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-05-01
• Completion: 2007-05-01
• First posted: 2007-08-02
• Last updated: 2009-03-31

Locations

1 site across 1 country: China