NCT00509314

The Mechanism of Melanocyte Self-Assembly on Biomaterials and the Functional Analysis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to survey melanocytes in the ability of self-assembly on biomaterials and functional analysis in vitro. Also, this study may provide a better way for treatment of vitiligo after understanding the functional aspects of melanocytes.

Detailed description

Vitiligo is a chronic disease that causes loss of melanocyte and pigment of the skin. Traditional treatments for vitiligo including topical corticosteroids and phototherapy lead to limited clinical effects. Autologous melanocyte transplantation is another way to treat vitiligo. However, the effect is largely affected by whether cultivated melanocytes are successfully uptaken by vitiliginous skin. The aim of this study is to survey the self-assembly on biomaterials and functional analysis. In the long run, this study may provide a better way for treatment of vitiligo.

Conditions

• Melanocyte
• Vitiligo

Interventions

Type	Name	Description
BEHAVIORAL	melanocyte self-assembly and functional analysis

Timeline

• Start date: 2006-05-01
• Completion: 2016-12-01
• First posted: 2007-07-31
• Last updated: 2007-07-31

Locations

1 site across 1 country: Taiwan