Clinical Trials Directory

Trials / Completed

CompletedNCT00509236

Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease (MK-0431-073 AM1)

A Multicenter, Randomized Double-Blind Study to Evaluate the Efficacy and Safety of Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease Who Are on Dialysis and Who Have Inadequate Glycemic Control

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
129 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
30 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to compare sitagliptin and glipizide in lowering blood sugar in participants with type-2 diabetes mellitus (T2DM) and end-stage renal disease on dialysis who do not have adequate glycemic control.

Conditions

Interventions

TypeNameDescription
DRUGSitagliptin25 mg (one 25-mg tablet) once daily
DRUGGlipizide2.5 mg (1/2 of a 5-mg tablet) once daily, up to 10 mg twice daily (four 5-mg tablets), for a maximum of 20 mg

Timeline

Start date
2007-10-19
Primary completion
2011-03-14
Completion
2011-03-14
First posted
2007-07-31
Last updated
2017-05-12
Results posted
2012-05-03

Source: ClinicalTrials.gov record NCT00509236. Inclusion in this directory is not an endorsement.