NCT00509132

A Tolerance and Pharmacokinetic Study of Trodusquemine in Healthy Volunteers

A Phase I, Double-Blind, Randomized, Placebo-Controlled Ascending IV Single-Dose Tolerance and Pharmacokinetic Study of Trodusquemine in Healthy Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 42 (estimated)
• Sponsor: Genaera Corporation · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the safety and tolerance of single intravenous (through a vein) doses of trodusquemine. Different amounts of trodusquemine will be given to each volunteer group throughout the study. Another purpose is to evaluate the pharmacokinetics (PK - the study of the way the drug enters and leaves the blood and tissues over time) of trodusquemine. Finally, this study will also determine whether trodusquemine has any effect on appetite, mood or behavior, and selective biomarkers (substances in your blood that may change in response to the study drug).

Conditions

• Obesity

Interventions

Type	Name	Description
DRUG	trodusquemine

Timeline

• Start date: 2007-05-01
• Primary completion: 2007-10-01
• Completion: 2007-10-01
• First posted: 2007-07-31
• Last updated: 2008-01-09

Locations

1 site across 1 country: United States