NCT00508781

Multiphoton Laser Scanning Microscopy in Cutaneous Optical Pathology

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 1 Year – 90 Years
• Healthy volunteers: Not accepted

Summary

We use multiphoton laser scanning microscopy to observe cutaneous anatomy and pathology. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy.

Detailed description

For skin diseases, the most convincing method for diagnosis to date is surgical biopsy. However, a skin biopsy is an invasive procedure which carries the risk of tissue damage, wound infection and scar formation. To solve the inconvenience from surgical biopsy, multiphoton laser scanning microscopy is a developing, non-invasive method for observing the cutaneous anatomy and pathology. Multiphoton laser scanning microscopy is good in tissue penetration and resolution with less tissue damage. The study aims to compare surgical specimen by conventional pathology slice with the image by non-invasive multiphoton laser scanning microscopy. A good correlation in multiphoton image may serve as optical biopsy for cutaneous pathology and spare the invasive procedure of skin biopsy.

Conditions

• Optical Biopsy
• Cutaneous Pathology
• Dermatopathology

Interventions

Type	Name	Description
BEHAVIORAL	Multiphoton laser image in cutaneous pathology

Timeline

• Start date: 2002-11-01
• Completion: 2012-12-01
• First posted: 2007-07-30
• Last updated: 2007-07-30

Locations

1 site across 1 country: Taiwan