Trials / Completed
CompletedNCT00507403
Infliximab and Methotrexate in Ankylosing Spondylitis
Effect of Methotrexate on the Relation Dose-effect of Infliximab in Ankylosing Spondylitis
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- University Hospital, Tours · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
There is a great individual variability of pharmacokinetic of infliximab in patients treated for ankylosing spondylitis (AS). Moreover, some patients have a treatment with methotrexate (MTX), others have not. Thus, the aim of this study is to assess the effect of MTX on the pharmacokinetic properties of infliximab in 30 patients treated for AS, 15 with MTX, 15 without.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | infliximab |
Timeline
- Start date
- 2007-10-01
- Primary completion
- 2009-10-01
- Completion
- 2009-12-01
- First posted
- 2007-07-26
- Last updated
- 2017-01-16
Locations
2 sites across 1 country: France
Source: ClinicalTrials.gov record NCT00507403. Inclusion in this directory is not an endorsement.