NCT00503178

Biological Imaging Guided Antalgic Radiotherapy of Bone Metastases (Phase II Trial)

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: University Hospital, Ghent · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

Highly selective irradiation requires accurate target definition by high-resolution three-dimensional imaging. Co-registration of FDG-PET and high-resolution CT might be the imaging modality of choice. This choice might target radiation therapy precisely to the intra-osseous volume that is responsible for pain and to spare selectively healthy bone in the vicinity of the metastasis. This strategy could result in equal anti-pain efficacy as conventional large volume radiotherapy, but could allow bone remodeling and preservation of bone structural strength in the vicinity and could lead to reduced toxicity to neighboring organs.

Conditions

• Bone Metastases

Interventions

Type	Name	Description
PROCEDURE	Biological imaging guided antalgic radiotherapy	Biological imaging guided antalgic radiotherapy is followed.

Timeline

• Start date: 2006-04-01
• Primary completion: 2015-04-22
• Completion: 2015-04-22
• First posted: 2007-07-18
• Last updated: 2022-12-22

Locations

1 site across 1 country: Belgium