Clinical Trials Directory

Trials / Completed

CompletedNCT00498797

E3-Hormone Refractory Prostrate Cancer Taxotere Combination

A Phase II, Double-blind, Placebo-controlled, Randomised Study to Assess the Efficacy and Safety of Docetaxel (Taxotere)/Prednisolone/ZD6474 vs Docetaxel/Prednisolone/Placebo in Patients With Hormone Refractory Prostrate Cancer (HRPC)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
86 (actual)
Sponsor
Sanofi · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether treatment with Zactima (vandetanib) in combination with Docetaxel and Prednisolone is more effective than the standard Docetaxel and Prednisolone alone for prostate cancer, in patients with Hormone refractory prostate cancer who have not previously received chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGZactima (vandetanib)
DRUGDocetaxel
DRUGPrednisolone

Timeline

Start date
2005-12-01
Primary completion
2007-07-01
Completion
2008-09-01
First posted
2007-07-10
Last updated
2016-10-07
Results posted
2011-05-24

Locations

11 sites across 5 countries: Brazil, Germany, Hungary, South Africa, Sweden

Source: ClinicalTrials.gov record NCT00498797. Inclusion in this directory is not an endorsement.