Clinical Trials Directory

Trials / Completed

CompletedNCT00496353

MK2461 Phase I/II Study in Patients With Advanced Solid Tumors (MK-2461-002 AM1)(COMPLETED)

A Phase I/II Dose Escalation and Proof-of-Concept Study of MK2461 in Patients With Advanced Solid Tumors

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
26 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purposes of this phase I portion are; 1) to evaluate the safety and tolerability of MK2461 and 2) to determine the recommended phase 2 dose or doses of MK2461. The purpose of the phase II portion is to evaluate the anti-tumor efficacy of MK2461.

Conditions

Interventions

TypeNameDescription
DRUGMK2461MK2461 treatment, bid, 28-day

Timeline

Start date
2007-06-01
Primary completion
2008-10-01
Completion
2008-11-01
First posted
2007-07-04
Last updated
2015-03-31

Source: ClinicalTrials.gov record NCT00496353. Inclusion in this directory is not an endorsement.

MK2461 Phase I/II Study in Patients With Advanced Solid Tumors (MK-2461-002 AM1)(COMPLETED) (NCT00496353) · Clinical Trials Directory