NCT00491140

Retrospective Study Assessing Molecular Features Predicting Response to Cetuximab

Retrospective Study Assessing Molecular Features Predicting Response or Resistance to Cetuximab Therapy in Metastatic Colorectal Cancer Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 85 (actual)
• Sponsor: Istituto Clinico Humanitas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective is to identify molecular features predicting response or resistance to cetuximab

Detailed description

Secondary objective is to investigate association of genomic status of EGFR and HER-2 genes with clinical outcome, including objective response, time to progression and survival

Conditions

• Colorectal Neoplasms

Interventions

Type	Name	Description
GENETIC	Gene mutations analysis and FISH	FISH and mutation analysis of multiple genes

Timeline

• Start date: 2006-12-01
• Primary completion: 2007-05-01
• Completion: 2008-06-01
• First posted: 2007-06-25
• Last updated: 2008-10-01

Locations

1 site across 1 country: Italy