Clinical Trials Directory

Trials / Terminated

TerminatedNCT00489658

Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, Uganda

Efficacy and Safety of an Eflornithine + Nifurtimox Combination for Treatment of Late-Stage Human African Trypanosomiasis (HAT) in West Nile, Uganda

Status
Terminated
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
31 (actual)
Sponsor
Epicentre · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This case series study follows on a terminated randomised clinical trial in a nearby location of Uganda, in which the combination of eflornithine + nifurtimox showed very promising efficacy and safety. The study's purpose is to evaluate the efficacy and safety of this combination in a larger group of late-stage Human African trypanosomiasis (sleeping sickness) patients.

Conditions

Interventions

TypeNameDescription
DRUGEflornithine plus Nifurtimox combination therapy

Timeline

Start date
2002-10-01
First posted
2007-06-21
Last updated
2007-06-21

Locations

1 site across 1 country: Uganda

Source: ClinicalTrials.gov record NCT00489658. Inclusion in this directory is not an endorsement.