Clinical Trials Directory

Trials / Completed

CompletedNCT00488787

Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain

A Randomized, Double-Blind, Placebo-Controlled Pilot Study of the Safety and Efficacy of 10 mg, 30 mg, and 50 mg of Transnasal Ketamine Hydrochloride (PMI-100) for the Treatment of Postoperative Dental Pain

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
40 (actual)
Sponsor
Javelin Pharmaceuticals · Industry
Sex
All
Age
16 Years
Healthy volunteers
Not accepted

Summary

Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo. Patients remain in the study unit for 3 hours post administration and assess pain intensity and pain relief throughout the 3 hour postoperative period.

Conditions

Interventions

TypeNameDescription
DRUGintranasal ketaminelow dose
DRUGintranasal ketaminemedium dose
DRUGintranasal ketaminehigh dose
DRUGplaceboplacebo

Timeline

Start date
2001-03-01
Primary completion
2001-04-01
Completion
2001-04-01
First posted
2007-06-20
Last updated
2008-02-07

Source: ClinicalTrials.gov record NCT00488787. Inclusion in this directory is not an endorsement.