NCT00487773

Effect of Different Doses of Budesonide on Markers of Bone Metabolism in Children With Asthma

Effect of Different Doses of Budesonide on Markers of Bone Metabolism in Children With Asthma - Randomized, Controlled Trial.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Medical University of Lodz · Academic / Other
• Sex: All
• Age: 5 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the trial is to check if inhaled glucocorticosteroids (iGCS) have influence on bone condition (if iGCS increases risk of osteoporosis and bone fraction) in children with asthma.

Detailed description

Asthma is the most prevalent chronic disease of respiratory tract, the largest frequency is noticed in children. iGCS are the basic group of drugs in asthma, because of inflammatory character of disease. All iGCS are absorbed to the systemic circulation (small amounts) despite of local exposition in lungs and possess systemic effects. The purpose of trial is to check if iGCS have influence on bone condition (if iGCS increases risk of osteoporosis and bone fraction) in children with asthma.

Conditions

• Asthma

Interventions

Type	Name	Description
DRUG	budesonide	budesonide
DRUG	D3 vitamin	D3 vitamin
DRUG	montelukast sodium	montelukast sodium
DRUG	salbutamol	salbutamol

Timeline

• Start date: 2007-09-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2007-06-19
• Last updated: 2010-04-13

Locations

1 site across 1 country: Poland