Clinical Trials Directory

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UnknownNCT00487253

Oral Miltefosine for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia

Randomized Clinical Trial of the Efficacy and Tolerability of Oral Miltefosine Versus Parenteral Antimony for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
Centro Internacional de Entrenamiento e Investigaciones Médicas · Academic / Other
Sex
All
Age
2 Years – 12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this randomized, open label clinical trial is to determine if oral miltefosine is a safe and effective alternative, compared with parenteral meglumine antimoniate for the treatment of pediatric Cutaneous caused by L. Viannia species in Colombia.

Conditions

Interventions

TypeNameDescription
DRUGMiltefosineOral Miltefosine, dosage 1,5mg -2,5mg/kg/day, during 28 days.
DRUGMeglumine antimoniateParenteral meglumine antimoniate Amp of 5ml (83mg/ml). Dosage: 20mg/kg/day one doses IM, during 20 days.

Timeline

Start date
2007-07-01
Primary completion
2010-02-01
Completion
2010-12-01
First posted
2007-06-18
Last updated
2010-02-17

Source: ClinicalTrials.gov record NCT00487253. Inclusion in this directory is not an endorsement.