NCT00485537

Pregnancy Outcomes With a GnRH Antagonist Protocol Versus GnRH-Agonist Protocol in ICSI Cycles

Pregnancy Outcomes With a Gonadotropin-Releasing Hormone (GnRH) Antagonist (Cetrorelix) Protocol Versus GnRH-Agonist Protocol in Ovarian Stimulation for ICSI Cycles-a Prospective Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,005 (actual)
• Sponsor: Clinic and Research Center in Human Reproduction Roger Abdelmassih · Academic / Other
• Sex: Female
• Age: 22 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Cycles with GnRH agonist and GnRH antagonist were compared and main outcome measures were the number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates, were analized.

Detailed description

160 women were equally divided between a GnRH antagonist protocol (Group 1) versus a GnRH agonist protocol (Group 2) in ICSI cycles. The trial was conducted between September 2005 and December 2006. The mean age in both groups was 32 (range 22-40). The main outcome measures were the number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates.

Conditions

• Infertility

Interventions

Type	Name	Description
PROCEDURE	oocyte retrieval and ICSI procedure

Timeline

• Start date: 2005-09-01
• Completion: 2006-12-01
• First posted: 2007-06-13
• Last updated: 2007-06-13

Locations

1 site across 1 country: Brazil