NCT00484705

Polycystic Ovary Syndrome (PCOS) - Effect Of Physical Exercise And Electroacupuncture

Polycystic Ovary Syndrome (PCOS) - The Female Metabolic Syndrome Genes And Processes In The Aetiology And Pathogenesis Of PCOS And Identification Of New Treatment Strategies

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Göteborg University · Academic / Other
• Sex: Female
• Age: 18 Years – 37 Years
• Healthy volunteers: Accepted

Summary

Hypothesis: The overall hypothesis is that women with PCOS, both obese and non-obese, have larger adipocytes, altered metabolism and signs of inflammation in adipose tissue and that these changes are associated with high sympathetic nerve activity, hyperandrogenism hyperinsulinaemia, insulin resistance with progression to type II diabetes and cardiovascular disease (CVD) as well as psychological distress and reduced quality of life. Physical exercise and electro-acupuncture decrease high concentrations of androgens, induce regulare menstrual pattern, inhibits high sympathetic activity and restore the PCOS induced disturbances.

Detailed description

Primary outcome: Changes in androgen concentrations and menstrual pattern Secondary outcome: changes in sympathetic nerve activity, uterus peristalsis, ovarian morphology, adipose tissue related variables, insulin sensitivity, coagulation factors and health related quality of life and symptoms of anxiety and depression.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
PROCEDURE	Electroacupuncture
PROCEDURE	Physical exercise
PROCEDURE	Untreated control

Timeline

• Start date: 2005-10-01
• Primary completion: 2008-10-01
• Completion: 2008-10-01
• First posted: 2007-06-11
• Last updated: 2009-11-10

Locations

1 site across 1 country: Sweden