NCT00484029

Nasal Carbon Dioxide (CO2)for the Treatment of Temporomandibular Disorders (TMD)Related Pain

A Randomized, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Nasal CO2 in the Symptomatic Treatment of Temporomandibular Disorders

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Capnia, Inc. · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This purpose of this study is to evaluate the safety and efficacy of treatment with nasal CO2 in the treatment of pain and other symptoms related to temporomandibular disorder (TMD).

Detailed description

This is a randomized, controlled trial evaluating the safety and efficacy of nasal carbon dioxide for the treatment of pain and other symptoms related to temporomandibular disorders (TMD). Approximately 115 men and women ages 18 to 70 years old who have a history consistent with TMD-related pain for at least 3 months and meet all other eligibility criteria will be enrolled in this study. There may be up to two (2) visits to the clinic, screening and treatment. Screening and treatment may occur on the same day.

Conditions

• Temporomandibular Disorders
• Pain
• Headaches

Interventions

Type	Name	Description
DRUG	Nasal Carbon Dioxide	Nasal Carbon Dioxide
OTHER	Air	Air (Medical Grade)

Timeline

• Start date: 2007-02-01
• Primary completion: 2008-10-01
• Completion: 2008-12-01
• First posted: 2007-06-08
• Last updated: 2010-08-20

Locations

1 site across 1 country: United States