Clinical Trials Directory

Trials / Completed

CompletedNCT00481455

Phase 2 Study of Panzem Nanocrystal Colloidal Dispersion (NCD) in Combination With Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme (GBM)

A Single-Center, Open-Label, Phase II, Safety and Efficacy Study of Panzem Nanocrystal Colloidal Dispersion Administered Orally in Combination With Protracted Oral Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
15 (actual)
Sponsor
CASI Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the anti-tumor activity and safety of Panzem NCD given in combination with daily oral fixed-dose temozolomide in patients with recurrent glioblastoma multiforme.

Conditions

Interventions

TypeNameDescription
DRUGPanzem NCD2000 mg q8h, continuous dosing in 28 day cycles
DRUGTemozolomideFixed dose

Timeline

Start date
2007-04-01
Primary completion
2007-09-01
Completion
2008-10-01
First posted
2007-06-01
Last updated
2008-11-25

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00481455. Inclusion in this directory is not an endorsement.