NCT00478491

fMRI of Vulnerable Brain Regions in Persons at Risk for Alzheimer's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 390 (actual)
• Sponsor: University of Wisconsin, Madison · Academic / Other
• Sex: All
• Age: 40 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate the organization of memory and develop future methods for early detection of AD. Using functional magnetic resonance imaging (fMRI), we examine the responsiveness of the brain to memory tasks, specifically focusing on regions of the brain (the mesial temporal lobe and posterior cingulate) that are known to be involved in early stages of Alzheimer's disease (AD). Of interest are differences in brain activation between people with and without a family history of AD and other risk factors.

Conditions

• Magnetic Resonance Imaging
• Alzheimer's Disease
• Dementia
• Adult Children
• Risk

Timeline

• Start date: 2003-01-01
• Primary completion: 2011-06-01
• Completion: 2011-07-01
• First posted: 2007-05-24
• Last updated: 2016-10-27

Locations

1 site across 1 country: United States