Clinical Trials Directory

Trials / Completed

CompletedNCT00477789

Effects of Allopurinol on Diastolic Function in Chronic Heart Failure Patients

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
Sponsor
Universita di Verona · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In patients with chronic heart failure (CHF)due to dilated cardiomyopathy diastolic dysfunction occurs frequently and is related to a poor outcome. We have previously shown that parameters of diastolic function significantly correlate with uric acid levels, a marker of impaired oxidative metabolism. We aimed to determine whether inhibition of xanthine oxidase with allopurinol might affect diastolic function in patients with CHF.

Conditions

Interventions

TypeNameDescription
DRUGallopurinol

Timeline

First posted
2007-05-24
Last updated
2007-05-24

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT00477789. Inclusion in this directory is not an endorsement.