Trials / Completed
CompletedNCT00476502
Study of Genetic Polymorphisms in Thai HIV-1 Infected Patients on SQV/r
Study of Genetic Polymorphisms of CYP 3A and MDR-1 Genes in Thai HIV-1 Infected Patients on Saquinavir/Ritonavir
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 250 (actual)
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Study of genetic polymorphisms of CYP #A and MDR-1 genes in Thai HIV-1 infected patients on saquinavir/ritonavir.
Detailed description
Genetic polymorphisms will be investigated by polymerase-chain reaction (PCR) and drug levels of saquinavir will be determined by high phase liquid chromatography with UV-detected (HPLC).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | identify genetic polymorphism in Thai HIV infected | Gene sequencing of Cyp450 metabolic pathway |
Timeline
- Start date
- 2006-02-01
- Primary completion
- 2008-12-01
- Completion
- 2008-12-01
- First posted
- 2007-05-22
- Last updated
- 2012-04-05
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT00476502. Inclusion in this directory is not an endorsement.