Trials / Completed
CompletedNCT00473980
Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
Preoperative Treatment With NSAID in Colorectal Cancer Patients in Relationship to Tumor Host Reactions
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 28 (actual)
- Sponsor
- Göteborg University · Academic / Other
- Sex
- All
- Age
- 40 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The study is designed to evaluate effects of NSAIDs on immune activity inside and close to tumor tissue in patients with colorectal cancer.
Detailed description
Study and control patients are randomized to receive preoperative treatment with indomethacin or celecoxib compared to sham treatment.Tumor biopsies are taken at operation and used for analyses of tumor immunity and gene expression.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Indomethacin, celecoxib, esomeprazole |
Timeline
- Start date
- 1998-12-01
- Completion
- 2007-05-01
- First posted
- 2007-05-16
- Last updated
- 2012-04-02
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT00473980. Inclusion in this directory is not an endorsement.