Clinical Trials Directory

Trials / Completed

CompletedNCT00473720

Phase I Study of the Combination of Satraplatin and Abraxane in Advanced Cancers

Phase I Dose Finding Study of the Orally Bioavailable Platinum Analog Satraplatin in Combination With Abraxane (Paclitaxel Protein-bound Particles) in Advanced Cancers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Yale University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a phase I dose escalating study of oral satraplatin in combination with Abraxane administered weekly for three out of every four weeks in patients with advanced solid cancers.

Conditions

Interventions

TypeNameDescription
DRUGSatraplatinDose escalation of 40, 60 and 80 mg/m²/day on days 1-5
DRUGAbraxaneDose escalation of 80 and 100 mg/mm²/day on days 1,8,15,22 every 28 days

Timeline

Start date
2007-05-01
Primary completion
2010-06-01
Completion
2010-06-01
First posted
2007-05-15
Last updated
2013-01-23

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00473720. Inclusion in this directory is not an endorsement.